Bacteria are micro-organisms that proliferate rapidly under favorable conditions of heat and humidity. Today, due to the spread of infectious diseases, the antibacterial effect of textiles as products that are in direct contact with the human body, and as the bacterial growth on the textiles results in bad odor, tissue damage, staining and discoloration, is very important. One of the most susceptible clothing for bacterial growth is socks. In addition to causing an unpleasant odor, foot transpiration causes the growth of bacteria and fungi among the fingers and infectious diseases. The warm, humid environment inside the shoe is also a good place for bacteria to grow. Bacteria feed on and propagate from dead skin cells of the foot and fat. Therefore, any action to prevent the growth and proliferation of bacteria will help maintain foot health. Nowadays, various methods, such as the use of nanoparticles for sock fabrication, are considered. The nanoparticles are contained in the full volume of the fibers and remain active for the entire sock life. Such socks do not cause an allergic reaction and do not harm the human body. Various nanoparticles such as silver, zinc or zycrobial have been considered in the manufacture of antibacterial clothing which, by reacting with the bacterium, causes structural changes within the bacterium and ultimately destroys it.